Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office

Published December 9, 2025
Updated December 10, 2025

Zachary Taylor, The President Whose Sudden Death Sparked Conspiracy Theories

Zachary Taylor A President Who Died In Office

Public DomainZachary Taylor was the second U.S. president to die in office.

Like William Henry Harrison, Zachary Taylor was a war hero who became president while in his 60s. And like Harrison, Taylor died suddenly.

A veteran of the Mexican-American War, Taylor had no strong political leanings — in fact, both the Whigs and the Democrats had weighed him as a presidential candidate — but when he was elected as a Whig in 1848, he took a stance on the big issues of the day. Taylor was pro-Union, and he threatened to take military action against any states that seceded. He also supported the highly controversial Wilmot Proviso, which proposed banning slavery in the new territory acquired during the Mexican-American War.

But then, in July 1850, Zachary Taylor fell ill.

Death Of Zachary Taylor

Public DomainA depiction of the death of Zachary Taylor, which occurred just over a year into Taylor’s term.

The president had reportedly spent the Fourth of July attending several celebrations, during which he consumed large amounts of cherries and iced milk. His thirst unquenched, Taylor then drank several glasses of water. He soon began to experience severe stomach pains, as well as nausea and diarrhea, which lasted for the next five days. And though Taylor’s doctors gave him ipecac, calomel, opium, and quinine, and even tried bleeding him, the president died on July 9, 1850, at the age of 65.

Taylor’s physicians believed he died of cholera morbus, a bacterial infection of the small intestine. Others have suggested that the president caught typhoid fever, or perhaps that he suffered from gastroenteritis from eating cherries combined with milk. But some believe that the president was murdered with arsenic to make way for Vice President Millard Fillmore.

Indeed, Fillmore went on to support the controversial Compromise of 1850, which made it easier for slave owners to pursue runaway slaves.

Millard Fillmore

Public DomainMillard Fillmore, the man who became president after Taylor’s sudden death.

So, was Taylor murdered? Taylor’s body was exhumed in 1991 to test for arsenic, but scientists found no evidence of foul play. Though some mystery remains around Zachary Taylor’s death, it seems that the president did indeed die of natural causes.

The first presidential assassination would not occur for another 15 years.

author
Kaleena Fraga
author
A senior staff writer for All That's Interesting since 2021 and co-host of the History Uncovered Podcast, Kaleena Fraga graduated with a dual degree in American History and French Language and Literature from Oberlin College. She previously ran the presidential history blog History First, and has had work published in The Washington Post, Gastro Obscura, and elsewhere. She has published more than 1,200 pieces on topics including history and archaeology. She is based in Brooklyn, New York.
editor
Jaclyn Anglis
editor
Based in Queens, New York, Jaclyn Anglis is the senior managing editor at All That's Interesting, where she has worked since 2019. She holds a Master's degree in journalism from the City University of New York and a dual Bachelor's degree in English writing and history from DePauw University. In a career that spans 11 years, she has also worked with the New York Daily News, Bustle, and Bauer Xcel Media. Her interests include American history, true crime, modern history, and science.
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Fraga, Kaleena. "Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office." AllThatsInteresting.com, December 9, 2025, https://allthatsinteresting.com/presidents-who-died-in-office. Accessed December 30, 2025.