Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office

Published December 9, 2025
Updated December 10, 2025

James Garfield, The President Who Died In Office 80 Days After He Was Shot

James Garfield A President Who Died In Office

Public DomainPresident James Garfield in 1881.

The next president who died in office was James Garfield. Like Lincoln, he was shot by an assassin. But unlike Lincoln, who died nine hours later, Garfield lingered between life and death for two months after he was fatally wounded.

In July 1881, Garfield had only been president for three months. A Union general during the Civil War and a former Republican congressman, Garfield had been elected as a “dark horse” candidate and was struggling to get his bearings in the White House. But in the early days of his administration, he’d attracted the attention of a mentally ill lawyer named Charles Guiteau.

Guiteau, seized by the delusion that he had played an important role in getting Garfield elected, decided to kill the president when Garfield failed to “reward” Guiteau for his “effort.” After buying a pistol he thought would look good in a museum, Guiteau learned that Garfield planned to take a train from the Baltimore and Potomac Station at around 9 a.m. on July 2, 1881. And there, Guiteau put his plan into action.

Assassination Of James Garfield

Public DomainA depiction of the assassination of James Garfield on July 2, 1881.

When Garfield entered the station with two of his sons and Secretary of State James G. Blaine, Guiteau pounced. He shot the president two times, first in the elbow and then in the lower back.

Guiteau was quickly apprehended, and Garfield, fatally wounded, seemed resigned to his fate. “I thank you, doctor,” he told one of the physicians who came to treat him, “but I am a dead man.”

The president’s doctors did not give up so easily — though they probably made the matter worse. Probing the wound in Garfield’s back with unwashed fingers in hopes of finding the bullet, they likely made the president more vulnerable to infection. Other treatments, including giving Garfield quinine, morphine, and alcohol — even champagne — only made Garfield sicker, and he slowly began to waste away.

Just over 11 weeks after his assassination, James Garfield died on Sept. 19, 1881, at the age of 49.

Charles Guiteau

Public DomainCharles Guiteau, the mentally ill failed lawyer who assassinated James Garfield.

His assassin, Guiteau, then tried to argue that the fault for the president’s death lay with Garfield’s doctors, not him, stating, “I did not kill the president. The doctors did that. I merely shot him.” But a jury found his argument unconvincing. Guiteau was hanged on June 30, 1882.

author
Kaleena Fraga
author
A senior staff writer for All That's Interesting since 2021 and co-host of the History Uncovered Podcast, Kaleena Fraga graduated with a dual degree in American History and French Language and Literature from Oberlin College. She previously ran the presidential history blog History First, and has had work published in The Washington Post, Gastro Obscura, and elsewhere. She has published more than 1,200 pieces on topics including history and archaeology. She is based in Brooklyn, New York.
editor
Jaclyn Anglis
editor
Based in Queens, New York, Jaclyn Anglis is the senior managing editor at All That's Interesting, where she has worked since 2019. She holds a Master's degree in journalism from the City University of New York and a dual Bachelor's degree in English writing and history from DePauw University. In a career that spans 11 years, she has also worked with the New York Daily News, Bustle, and Bauer Xcel Media. Her interests include American history, true crime, modern history, and science.
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Fraga, Kaleena. "Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office." AllThatsInteresting.com, December 9, 2025, https://allthatsinteresting.com/presidents-who-died-in-office. Accessed December 30, 2025.