Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office

Published December 9, 2025
Updated December 10, 2025

The Death Of Franklin D. Roosevelt After Serving 12 Years As President

Last Photo Of Franklin Roosevelt

Public DomainThe last photo of President Franklin Roosevelt, taken one day before his death in 1945.

Franklin Roosevelt was one of the most consequential presidents in American history. Elected in 1932, he guided the nation through both the Great Depression and World War II. For some young Americans, Roosevelt was the only president they’d ever known. But on April 12, 1945, Roosevelt became the seventh president who died in office.

By then, Roosevelt was 63 years old and feeling the pressures of the presidency more than ever. His election to a fourth term in office in 1944 and his negotiation of the fate of post-war Europe at the Yalta Conference in 1945 had drained him. So, in April 1945, Roosevelt decided to recover in Warm Springs, Georgia, alongside his mistress, Lucy Mercer Rutherfurd.

The president was sitting for a portrait on the afternoon of April 12, 1945, when he suddenly felt ill. Roosevelt exclaimed, “I have a terrific headache,” then slumped forward in his chair. At 3:35 p.m., the president died.

Unfinished Portrait Of Franklin Roosevelt

Elizabeth ShoumatoffFranklin Roosevelt died while his portrait was being painted by artist Elizabeth Shoumatoff.

Roosevelt had succumbed to a stroke after suffering from health ailments like high blood pressure, congestive heart failure, and possible melanoma, as well as the lingering effects of his polio.

But though the president had been ill, his death came as a shock to Americans — and the rest of the world. Winston Churchill described Roosevelt’s death as “a physical blow.” And his vice president, Harry S. Truman, exclaimed that the president’s death felt like “the Moon, the stars, and all the planets had fallen on me.”

Indeed, Truman had rarely been included in Roosevelt’s administration. On the night of the president’s death, he was informed for the first time of a “new explosive of almost unbelievable destructive power” — the atomic bomb — which Truman would deploy on Japan later that year.

author
Kaleena Fraga
author
A senior staff writer for All That's Interesting since 2021 and co-host of the History Uncovered Podcast, Kaleena Fraga graduated with a dual degree in American History and French Language and Literature from Oberlin College. She previously ran the presidential history blog History First, and has had work published in The Washington Post, Gastro Obscura, and elsewhere. She has published more than 1,200 pieces on topics including history and archaeology. She is based in Brooklyn, New York.
editor
Jaclyn Anglis
editor
Based in Queens, New York, Jaclyn Anglis is the senior managing editor at All That's Interesting, where she has worked since 2019. She holds a Master's degree in journalism from the City University of New York and a dual Bachelor's degree in English writing and history from DePauw University. In a career that spans 11 years, she has also worked with the New York Daily News, Bustle, and Bauer Xcel Media. Her interests include American history, true crime, modern history, and science.
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Fraga, Kaleena. "Inside The Tragic Stories Of The Eight U.S. Presidents Who Have Died In Office." AllThatsInteresting.com, December 9, 2025, https://allthatsinteresting.com/presidents-who-died-in-office. Accessed December 30, 2025.