Beginning in the 1990s, the Long Island Serial Killer was suspected of murdering between 10 and 16 people and discarding them near Gilgo Beach in New York.

On August 10, 1991, employees at the Sheraton Hotel in Martinsburg, West Virginia found freelance journalist Danny Casolaro dead in room 517 — but who killed him?

The 1976 Chowchilla school bus kidnapping saw 26 California children abducted, buried alive, and held for ransom — then they miraculously escaped.

On November 24, 1991, Queen frontman Freddie Mercury died in his London home of AIDS complications just 24 hours after revealing his diagnosis.

In January 2003, Susan Wright stabbed her husband Jeff 193 times, later claiming that she snapped after suffering years of physical abuse from him.

Christian Longo brutally murdered his wife and three young children in 2001 — all because he was trying to cover up his financial difficulties and fraudulent lifestyle.

Union Army Major Henry Rathbone spent his life wracked with guilt after he wasn't able to stop John Wilkes Booth, causing his mental health to eventually deteriorate so much that he murdered his wife in 1883.

In November 2004, 21-year-old Christopher Porco chopped up his parents as they slept in their bed, leaving his father dead and his mother missing an eye and part of her skull.

Tilly Devine started out as an impoverished sex worker in the London slums before she moved to Australia, opened a string of successful brothels, and became one of the most violent crime bosses in Sydney.

Dubbed the "Girl in the Closet," Lauren Kavanaugh was isolated and abused mentally, physically, and sexually by her mother and stepfather between the ages of two and eight.

Frank Lloyd Wright built a house called Taliesin as a refuge for his mistress Mamah Borthwick. But in 1914, one of his servants butchered her with an ax and burned the Wisconsin home down.

George Hodel was a notorious Los Angeles doctor whose sexual proclivities and surgical knowledge have led many to believe that he killed Elizabeth Short.